Eczema is an umbrella term that encompasses a number of inflammatory skin conditions that produce very dry, itchy skin and rashes on various parts of the body. The National Eczema Association estimates that over 30 million Americans have a form of eczema, such as atopic dermatitis, contact dermatitis, or seborrheic dermatitis. Eczema triggers can include shampoo, body washes, laundry detergent, food, pollen, dust mites, pet dander, as well as the climate, hormones, and even stress. But traditional therapy might not be the only way to manage flares. While there is no cure for eczema, eczema flares are sometimes triggered by an allergic reaction to specific foods, suggesting some people with eczema can benefit from following diets tailored to their allergies. Other dietary interventions, such as regularly drinking water to keep the body and skin hydrated, may also reduce eczema flares and symptoms. In , 5. Food allergies are the result of an abnormal immune system response after eating certain foods.
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Food allergy caused by nickel was first suspected when dermatologists noticed that some people exhibited symptoms of dermatitis on skin surfaces that were not in contact with any known allergen. These dermatologists suspected that the allergenic source might be in something ingested and looked for sources of known contact allergens, such as nickel, in commonly eaten foods. Nickel occurs naturally in many foods and may be introduced during food processing—for example, from metal containers or cooking utensils. Nickel is a well-known cause of contact dermatitis in nickel-sensitive people, inducing a reaction wherever it is in close contact with the skin or mucous membrane for a period of time. This response is known as a cell-mediated delayed previously type IV hypersensitivity reaction. The nickel induces local T-cell lymphocytes to produce cytotoxic cytokines that cause the itching, reddening and scaling of contact dermatitis. The relationship between nickel and food as a cause of allergic reaction is less well understood. Symptoms Nickel-contact dermatitis develops in areas in direct contact with nickel-containing objects such as jewellery, metal studs and watchbands and in occupations where metal contact is frequent. Ingested dietary nickel may trigger reactions in the skin in individuals who react to systemically to nickel. Eczema, especially on the hands, may develop as a secondary response to nickel sensitization. The eczematous rash may later spread to other body surfaces.