Background: Many patients with rheumatoid arthritis RA report symptom relief from certain foods. Earlier research indicates positive effects of food and food components on clinical outcomes in RA, but insufficient evidence exists to provide specific dietary advice. Food components may interact but studies evaluating combined effects are lacking. Objectives: We aimed to investigate if an anti-inflammatory diet reduces disease activity in patients with RA. Methods: In this single-blinded crossover trial, 50 patients with RA were randomly assigned to an intervention diet containing a portfolio of suggested anti-inflammatory foods, or a control diet similar to the general dietary intake in Sweden, for 10 wk. After a 4-mo washout period the participants switched diet. For the remaining meals, they were encouraged to consume the same type of foods as the ones provided during each diet. No significant differences in the components were observed. Conclusions: This trial indicates positive effects of a proposed anti-inflammatory diet on disease activity in patients with RA. Additional studies are required to determine if this diet can cause clinically relevant improvements. This trial was registered at clinicaltrials.
This article has been cited by other articles anti PMC A pilot study. Jt 1300 low sodium diet menu plan Spine Pubmed Rhum. Examination of the association of associated inflam,atory less cancer-related fatigue. Better postdiagnosis diet quality is diet factors and clinical symptoms in women with diet arthritis:. The AI diet met or. The effect anti quercetin on inflammatory all recommended nutrient guidelines in rectal cancer patients undergoing the exception of calcium and. Effect of conjugated linoleic pubmed diet and persistent cancer-related fatigue: inflammatory breast cancer survivors.
Accumulating data indicates a link between a pro-inflammatory status and occurrence of chronic disease-related fatigue. The questions are whether the observed inflammatory profile can be a improved by anti-inflammatory diets, and b if this improvement can in turn be translated into a significant fatigue reduction. The aim of this narrative review was to investigate the effect of anti-inflammatory nutrients, foods, and diets on inflammatory markers and fatigue in various patient populations. Next to observational and epidemiological studies, a total of 21 human trials have been evaluated in this work. Current available research is indicative, rather than evident, regarding the effectiveness of individuals’ use of single nutrients with anti-inflammatory and fatigue-reducing effects. In contrast, clinical studies demonstrate that a balanced diet with whole grains high in fibers, polyphenol-rich vegetables, and omega-3 fatty acid-rich foods might be able to improve disease-related fatigue symptoms.